Application A1226 - Food derived from insect-protected corn line MON95379 (Supporting Document)

Application A1226 seeks approval for the sale and use of food derived from genetically modified (GM) corn line MON95379 that is protected against parasitic lepidopteran insect pests. Protection against lepidopteran insect pests is conferred by the expression in the plant of two novel Bacillus thuringiensis crystal (Cry) proteins: Cry1B.868 encoded by the cry1B.868 gene and Cry1Da_7 encoded by the cry1Da_7 gene. These novel substances cause midgut damage specifically in lepidopteran larvae, such as fall armyworm and corn earworm larvae. While FSANZ has assessed and approved numerous B. thuringiensis Cry proteins in a variety of plant species, the cry1B.868 and cry1Da_7 genes have not previously been assessed by FSANZ.